Updated: Apr 4, 2020
JANSSEN HAS ANNOUNCED THAT DARUNAVIR HAS NO ANTIVIRAL ACTIVITY AGAINST NOVEL CORONAVIRUS
Janssen has announced that there was no clinical or pharmacological evidence available which suggests the use of darunavir against novel coronavirus. The company has announced that it has assessed the in-vitro antiviral activity of darunavir. However, the compound has no activity against SARS-CoV-2.
The company has also announced that it is testing other antivirals for the activity against the novel coronavirus.
Are you working from home?
Ministry of Health, Italy, has some suggestions for you.
Ministry of Health recommended calorie intake as follows:
Morning snack 5%
Afternoon snack 5%
Drink plenty of water
Limit the use of salt and sugar
Consume foods that provide at least 25 grams of dietary fiber per day
Includes milk or yogurt in the breakfast and a baked product
Avoid skipping meals
Consume at least five portions a day between fruit and vegetables (preferably 2 of fruit and 3 of vegetables)
Fruit juice, even 100%, never replaces fresh fruit
Consume cereals (bread, pasta, rice, etc.) daily
Eat fish at least 2-3 times a week, fresh or frozen
Prefer white meat, and reduce the consumption of red meat
Limit consumption of high-fat foods, salt, sugar, and sugary drinks
There is no safe and recommendable for alcohol. For good health, it is better to avoid alcohol
Physical activity for children
Infants (under one year of life) should move several times a day
1-2-year-olds should spend at least 180 minutes in moderate to vigorous physical activity
3-4-year-olds should spend at least 180 minutes in movement. They should be engaged in different types of physical activity, including at least 60 minutes of moderate to vigorous-intensity activity
Children and adolescents aged between 5 and 17 should practice at least 60 minutes of daily physical activity of moderate to vigorous intensity
Physical activity for adults
WHO recommendations are:
a minimum of 150 minutes per week of aerobic activity with moderate intensity or
a minimum of 75 minutes of vigorous activity plus strengthening exercises
EMA advised patients to continue treatment of hypertension with angiotensin converting enzyme (ACE) inhibitors and angiotensin receptor blockers
EMA has released the press release after the media reports stating that the treatment with angiotensin converting enzyme (ACE) inhibitors and angiotensin receptor blockers might worsen COVID-19 condition.
However, EMA has clarified that there are no clinical or epidemiological studies which support this data.
The drugs (angiotensin converting enzyme (ACE) inhibitors and angiotensin receptor blockers) act on renin-angiotensin-aldosterone system (RAAS), whereas the virus act on angiotensin converting enzyme 2 (ACE2), which is part of this system. But there are no studies support the interaction of virus with the drugs.
Abbott launches test to detect novel coronavirus in less than five minutes
The Abbott ID NOW COVID-19 test has been approved by the US Food and Drug Administration for testing Coronavirus.
The positive results can be displayed within five minutes and the negative results takes as much as 13 minutes, as per the company.
ID NOW is a rapid, instrument-based, isothermal system is used in the detection of infectious diseases.
The kit has been approved under Emergency Use Authorization (EUA) but has not been FDA or EMA cleared.