top of page

Deals and Acquisitions | 2023 | Pharma | News | Healthcare | iPharmaCenter

Updated: Apr 19

Merck announced that it had entered an agreement to acquire Prometheus Biosciences.

Merck aims to strengthen its immunology portfolio through this acquisition by adding a potential first-in-class therapy for inflammatory bowel disease (IBD) and other immunological conditions.

Also read: Top pharmaceutical companies of 2023

Merck will acquire by paying $200 per share; the acquisition is expected to cost $10.8 billion. Prometheus Biosciences' lead candidate, PRA023, is a monoclonal antibody that targets the tumor necrosis factor (TNF)-like ligand 1A (TL1A), a key mediator of inflammation in IBD. The acquisition is expected to complete by the third quarter of 2023.

Also read: China Drug Approvals

Pfizer and Seagen have announced an agreement under which Pfizer will acquire Seagen for $229 in cash per share, valued at nearly $43 billion.

Pfizer is aiming that Seagen's expertise in Antibody-Drug Conjugates (ADCs) can strengthen Pfizer's oncology portfolio. Further, it is estimated that Seagen will add $10 billion in revenues by 2030. In 2023, the expected revenues from Seagen were $2.2 billion. Pfizer Oncology's portfolio has 24 approved therapies generating $12.1 billion in revenues.

Seagen's currently approved therapies include Adcetris, Padcev, Tivdak, and Tukysa. It further has eleven new molecular entities in the pipeline.

Also read: Pharmaceutical deals and acquisitions

Sanofi has announced its intention to acquire Provention Bio, a U.S.-based biopharmaceutical company, for $2.9 billion. The acquisition will add Provention Bio's first-in-class therapy in type 1 diabetes, Tzield (teplizumab), to Sanofi's portfolio. Tzield was approved in the US last year as the first and only therapy to delay the onset of stage 3 type 1 diabetes in adults and pediatric patients aged eight years and older with stage 2 T1D.

Also read: Drug approvals in Europe

Sanofi's stated that the acquisition of Provention Bio aligns with the company's strategic shift towards developing products that have a unique profile in treating immune-mediated diseases and disease-modifying therapies, especially in areas with high unmet needs. Additionally, the acquisition is consistent with Sanofi's expertise in diabetes.

Sanofi announced that it would commence a cash tender offer to acquire Provention Bio's shares for $25.0 per share in cash, valued at approximately 2.9 billion.

  • With the acquisition, AstraZeneca will get access to aldosterone synthase inhibitor baxdrostat.

  • Baxdrostat is in Phase 2 for hyperaldosteronism and hypertension.

AstraZeneca announced that it would acquire a US-based clinical-stage biopharmaceutical company, CinCor Pharma, developing novel treatments for resistant and uncontrolled hypertension and chronic kidney disease.

With the acquisition, AstraZeneca aims to strengthen its cardiorenal portfolio with baxdrostat (CIN-107), an aldosterone synthase inhibitor (ASI) for resistant hypertension.

Also read: HAS Assessment outcomes

For this acquisition, AstraZeneca offered to pay $26 per share, followed by $10 per share upon successful regulatory submission of baxdrostat. The upfront payment represents a value of $1.3 billion. With the regulatory submission, the transaction value can reach $1.8 billion.

Also read: NICE Assessment Outcomes


Recent Posts

See All

GlaxoSmithKline (GSK) has presented positive results from the phase III trial of its MenABCWY vaccine candidate at the European Society for Paediatric Infectious Diseases. The vaccine combination was